MA5-15505 targets TYRO3 in WB applications and shows reactivity with Human samples.
The MA5-15505 immunogen is purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.
MA5-15505 detects TYRO3 which has a predicted molecular weight of approximately 96.9kDa.
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Brt; BYK; Dtk; FLJ16467; RSE; Sky; Tif; TYRO3; Tyrosine-protein kinase BYK; Tyrosine-protein kinase DTK; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Aliases: BYK; DTK; Etk-2; Rek; RSE; SKY; TIF; TYRO3
UniProt ID: (Human) Q06418
Entrez Gene ID: (Human) 7301