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|Tested species reactivity||Human|
|Published species reactivity||Sheep, Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Recombinant protein corresponding to N-terminal region of human TRAP|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 3 publications below|
MA5-12387 targets Tartrate Resistant Acid Phosphatase in IHC (P) applications and shows reactivity with Human samples.
The MA5-12387 immunogen is recombinant protein corresponding to N-terminal region of human TRAP.
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A new piezoelectric actuator induces bone formation in vivo: a preliminary study.
MA5-12387 was used in immunohistochemistry to study the use of a novel piezoelectric device to mechanically stimulate bone formation
|Reis J,Frias C,Canto e Castro C,Botelho ML,Marques AT,Simões JA,Capela e Silva F,Potes J||Journal of biomedicine & biotechnology (2012:null)||2012|
Loss of osteoclasts contributes to development of osteosarcoma pulmonary metastases.
MA5-12387 was used in immunohistochemistry to study the role of osteoclast loss in the development of osteosarcoma pulmonary metastases
|Endo-Munoz L,Cumming A,Rickwood D,Wilson D,Cueva C,Ng C,Strutton G,Cassady AI,Evdokiou A,Sommerville S,Dickinson I,Guminski A,Saunders NA||Cancer research (70:7063)||2010|
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
MA5-12387 was used in immunohistochemistry to report on two cases of giant cell tumor-like lesion of the urinary bladder
|Behzatoğlu K,Durak H,Canberk S,Aydin O,Huq GE,Oznur M,Ozyalvaçli G,Yildiz P||Diagnostic pathology (4:null)||2010|
human purple acid phosphatase; tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; tartrate-resistant acid phosphatase type 5; TRAPase; TrATPase
ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase