MA5-12387 targets Tartrate Resistant Acid Phosphatase in IHC (P) applications and shows reactivity with Human samples.
The MA5-12387 immunogen is recombinant protein corresponding to N-terminal region of human TRAP.
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
Protein Aliases: human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
Gene Aliases: ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase
UniProt ID: (Human) P13686
Entrez Gene ID: (Human) 54