|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from human TAS2R4 conjugated to an immunogenic carrier protein was used as the antigen|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
This product ships at ambient temperature.
Reconstitute in 100 µl of sterile water.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunohistochemical detection of TAS2R38 protein in human taste cells.
OSR00153W was used in immunocytochemistry to study the localization of human bitter taste receptor TAS2R38
|Behrens M,Born S,Redel U,Voigt N,Schuh V,Raguse JD,Meyerhof W||PloS one (7:null)||2012|