PN1000 targets Tau in IHC, and WB applications and shows reactivity with Bovine, Human, and Rat samples.
The PN1000 immunogen is purified human tau.
PN1000 detects Tau which has a predicted molecular weight of approximately 79 kDa.
This product is a Low Endotoxin formulation.
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.