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Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:5,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Bacteria |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226aa) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
4.95 mg/mL |
Purification |
Protein G |
Storage buffer |
10mM PBS, pH 7.4, with 50% glycerol |
Contains |
0.03% ProClin 300 |
Storage conditions |
-20°C or -80°C if preferred |
RRID |
AB_2902154 |
This antibody has been tested in direct-ELISA
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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