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Product Details
TKV-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequences on pan Thickvein protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Mutants of the thick veins (tkv) gene have been described previously (as slater alleles) as embryonic lethal, lacking dorsal epidermis, but not as showing a recognizable dorsoventral phenotype. The maternal alteration of function coupled with zygotic reduction of function of tkv is strongly ventralizing. In double heterozygous combinations in the mother, tkv mutations increase the ventralizing effect of dominant, weakly ventralizing alleles of the maternal effect, dorsoventral genes easter and cactus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activin-A-receptor-25D; BMP receptor kinase 25D; CG14026-PA; CG14026-PB; CG14026-PC; CG14026-PD; DPP receptor; GH25238p; Receptor protein serine/threonine kinase; slater; thick veins; Thick-vein; Thick-veins; thickvein; tkv; tkv-PA; tkv-PB; tkv-PC; tkv-PD
Gene Aliases: Atkv; Atr25D; Brk25D; Brk25D1; Brk25D2; CG14026; Dmel\CG14026; Dmel_CG14026; Dtfr; kv; l(2)04415; l(2)25Da; STK-A; str; TKV; TKV1; tkva
Entrez Gene ID: (Fruit fly) 33753
compound eye morphogenesis
protein phosphorylation
neuromuscular synaptic transmission
amnioserosa formation
dorsal closure
open tracheal system development
anterior/posterior pattern specification, imaginal disc
imaginal disc-derived wing morphogenesis
histoblast morphogenesis
heart development
germ cell migration
dorsal/ventral pattern formation
cell migration
regulation of cell-cell adhesion
BMP signaling pathway
ovarian follicle cell development
germ-line stem cell population maintenance
spectrosome organization
genital disc development
wing disc pattern formation
germ-line stem cell division
R8 cell fate specification
regulation of imaginal disc growth
regulation of cell differentiation
negative regulation of salivary gland boundary specification
positive regulation of synaptic growth at neuromuscular junction
positive regulation of growth
dorsal closure, amnioserosa morphology change
wing disc anterior/posterior pattern formation
positive regulation of muscle organ development
SMAD protein signal transduction
transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification
anterior Malpighian tubule development
cellular response to growth factor stimulus
cell elongation involved in imaginal disc-derived wing morphogenesis
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