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Formalin-fixed, paraffin-embedded human papillary thyroid carcinoma stained with Thyroid Cancer Marker antibody with AEC chromogen. Note staining of cytoplasm and apical cell surface of tumor cells as well as intraluminal space and membrane and cytoplasmic stain of PTC.
|Tested species reactivity||Human|
|Host / Isotype||Mouse|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Papillary carcinoma is by far the most frequent malignant tumor of the thyroid with a threefold prevelance in females. Studies have shown that 100% of malignant thyroid lesions were found to contain the keratan sulfate (KS) bearing molecules, while these were virtually absent from benign tissues and other thyroid tumors, with the exception of 21% of follicular carcinoma cases analyzed1. Clone 373E1 is specific for the keratan sulfate bearing molecular complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.