|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 251 of Human Thyroid Hormone Receptor alpha 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
PA5-29618 targets Thyroid Hormone Receptor alpha 2 in IF and WB applications and shows reactivity with Human samples.
The PA5-29618 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 251 of Human Thyroid Hormone Receptor alpha 2.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog; AR7; avian); c-ERBA-1; c-erbA-alpha; CHNG6; EAR-7; EAR7; ERB-T-1; ERBA; ERBA-related 7; ERBA1; NR1A1; nuclear receptor subfamily 1 group A member 1; THRA1; THRA2; thyroid hormone receptor; thyroid hormone receptor alpha; thyroid hormone receptor alpha 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); thyroid normone nucle; thyroid normone nuclear receptor alpha variant 1; triiodothyronine receptor; V-erbA-related protein 7
AR7; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA; THRA1; THRA2