|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG|
|Immunogen||synthetic peptide VAPGLVRYRHHERLC, corresponding to amino acids 44-58 of Human Tin2.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-91513 detects Tin2 from human samples.
MA1-91513 has been successfully used in Western blot applications.
The MA1-91513 immunogen is: Synthetic peptide: VAPGLVRYRHHERLC, corresponding to amino acids 44-58 of Human Tin2.
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.