|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human Tissue Factor Pathway Inhibitor.|
|Purification||Ion-exchange chromatography, Ammonium sulfate precipitation|
|Storage buffer||50% water with 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||5-10 µg/mL|
|Western Blot (WB)||5-10 µg/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-43059 detects Tissue Factor Pathway Inhibitor in human samples.
PA1-43059 has successfully been used in Western blot and ELISA applications.
PA1-43059 was derived from human tissue factor pathway inhibitor.
TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.