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|Tested species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (179 SRRGIRYRSIDEHDAII 195) of Tmem123 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||5-8 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Transmembrane protein 123, or Tmem123, is a single-pass type I membrane protein and belongs to the CD164 family. Tmem123 acts as a novel marker for DC maturation. DCs are also known as professional antigen-presenting cells. It is reported that the Tmem123 molecule may be closely associated with the cell surface expression of CD40. It was also reported previously that Tmem123 protein may also be responsible for oncotic cell death, which is characterized by cell swelling, organelle swelling, vacuolization, increased membrane permeability and cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
KCT-3; KCT3; keratinocytes associated transmembrane protein 3; keratinocytes-associated transmembrane protein 3; PORIMIN; PORMIN; pro oncosis receptor inducing membrane injury; pro-oncosis receptor inducing membrane injury; PSEC0111; serine/threonine-rich receptor