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Product Details
PA5-65651
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Torsin 1A. Recombinant protein control fragment (Product #RP-106327).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662036
Product Specific Information
Immunogen sequence: QAVEPISLGLA LAGVLTGYIY PRLYCLFAEC CGQKRSLSRE ALQKDLDDNL FGQHLAKK
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 92%.
Target Information
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; dystonia 1, torsion (autosomal dominant; torsin A); Torsin 1A; torsin A; torsin ATPase 1; Torsin ATPase-1A; Torsin family 1 member A; torsin family 1, member A (torsin A); Torsin-1A
Gene Aliases: DQ2; DYT1; TA; TOR1A; TORA
UniProt ID: (Human) Q96CA0
Entrez Gene ID: (Human) 1861
protein deneddylation
response to oxidative stress
organelle organization
nuclear envelope organization
cell adhesion
neuron projection development
protein localization to nucleus
wound healing, spreading of cells
intermediate filament cytoskeleton organization
synaptic vesicle transport
chaperone mediated protein folding requiring cofactor
protein homooligomerization
regulation of dopamine uptake involved in synaptic transmission
chaperone-mediated protein folding
ER-associated misfolded protein catabolic process
nuclear membrane organization
chaperone-mediated protein transport
positive regulation of synaptic vesicle endocytosis
regulation of protein localization to cell surface
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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