|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1.0 ug/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
MA5-17920 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.
The MA5-17920 immunogen is mouse CD71.
Cell surface transferrin receptor (CD71) is a disulfide-bonded homodimeric glycoprotein. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor (CD71) has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.
MA5-17920 was used in flow cytometry to report two Treg subsets with distinct phenotypes and homeostasis in normal unmanipulated mice.
|Fisson S,Darrasse-Jèze G,Litvinova E,Septier F,Klatzmann D,Liblau R,Salomon BL||The Journal of experimental medicine (198:737)||2003|