|Tested species reactivity||Bovine, Human, Mouse, Rat|
|Published species reactivity||Hamster, Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-13904 targets Transforming Growth Factor alpha in WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples.
The MA5-13904 immunogen is a 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha.
TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Central precocious puberty due to hypothalamic hamartomas correlates with anatomic features but not with expression of GnRH, TGFalpha, or KISS1.
MA5-13904 was used in immunohistochemistry to investigate the gene expression and other characteristics of hypothalamic hamartomas
|Chan YM,Fenoglio-Simeone KA,Paraschos S,Muhammad L,Troester MM,Ng YT,Johnsonbaugh RE,Coons SW,Prenger EC,Kerrigan JF,Seminara SB||Hormone research in paediatrics (73:312)||2010|
Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils.
MA5-13904 was used in immunohistochemistry to investigate the changes of mucous cells in cystic fibrosis
|Hays SR,Fahy JV||American journal of respiratory and critical care medicine (174:1018)||2006|
Transforming growth factor-alpha is expressed in astrocytes of the suprachiasmatic nucleus in hamster: role of glial cells in circadian clocks.
MA5-13904 was used in immunohistochemistry to investigate the effect of glial cells on the regulation of suprachiasmatic nucleus circadian clock
|Li X,Sankrithi N,Davis FC||Neuroreport (13:2143)||2002|
A functional role for EGFR signaling in myelination and remyelination.
MA5-13904 was used in western blot to study the role of EGFR signaling in myelination and remyelination
|Aguirre A,Dupree JL,Mangin JM,Gallo V||Nature neuroscience (10:990)||2007|
Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration.
MA5-13904 was used in western blot to investigate the role of heparin-binding epidermal growth factor-like growth factor on hepatocytic regeneration
|Mitchell C,Nivison M,Jackson LF,Fox R,Lee DC,Campbell JS,Fausto N||The Journal of biological chemistry (280:2562)||2005|