Immunocytochemistry analysis of cardiomyocyte primary cells stained with ABfinity™ TNNT2 Recombinant Rabbit Oligoclonal antibody (2.5 µg/mL) showing a: Alexa Fluor® 488 goat anti-rabbit secondary antibody (green), b: DAPI stained cardiomyocyte primary cell nuclei (blue), c: actin stained with Alexa Fluor® 594 Phalloidin (red), d: composite image of cells showing structural muscle filament localization of TNNT2, e: no primary control.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunocytochemistry (ICC)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.