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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 176 and 451 of Human Tryptophanyl tRNA synthetase|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29849 targets Tryptophanyl tRNA synthetase in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-29849 immunogen is recombinant fragment corresponding to a region within amino acids 176 and 451 of Human Tryptophanyl tRNA synthetase.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cytoplasmic; GAMMA-2; hWRS; IFI53; IFP53; interferon-induced protein 53; trpRS; tryptophan tRNA ligase 1; tryptophan tRNA ligase 1, cytoplasmic; tryptophan--tRNA ligase; tryptophan--tRNA ligase, cytoplasmic; tryptophanyl-tRNA synthetase, cytoplasmic
GAMMA-2; IFI53; IFP53; TrpRS; WARS; WRS