This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MA5-14177 targets Tyrosinase in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples.
The MA5-14177 immunogen is recombinant tyrosinase protein.
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Albino locus protein; LB24-AB; Monophenol monooxygenase; oculocutaneous albinism IA; SK29-AB; Tumor rejection antigen AB; Tyrosinase
Gene Aliases: albino; ATN; c; CMM8; OCA1; OCA1A; OCAIA; SHEP3; skc35; TYR