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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||SK-MEL-23 Melanoma cell line|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12293 targets Tyrosinase Related Protein 75 in IHC (F) and WB applications and shows reactivity with Human samples.
The MA5-12293 immunogen is sK-MEL-23 Melanoma cell line.
Tyrosinase related Protein 75 (TRP75/gp75) is a pigmentation associated proteins expressed by melanoma cells and normal melanocytes. This antigen appears to be expressed during the stage III and IV of melanosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.
MA5-12293 was used in immunocytochemistry to study the proteolytic release of glycoprotein nonmetastatic melanoma protein b from melanosomes
|Hoashi T,Sato S,Yamaguchi Y,Passeron T,Tamaki K,Hearing VJ||FASEB journal : official publication of the Federation of American Societies for Experimental Biology (24:1616)||2010|
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
MA5-12293 was used in flow cytometry to examine the allogenic glioma cells for the generation of therapeutic vaccines or cellular therapy
|Zhang JG,Eguchi J,Kruse CA,Gomez GG,Fakhrai H,Schroter S,Ma W,Hoa N,Minev B,Delgado C,Wepsic HT,Okada H,Jadus MR||Clinical cancer research : an official journal of the American Association for Cancer Research (13:566)||2007|
5; 6-dihydroxyindole-2-carboxylic acid oxidase; catalase B; DHICA oxidase; glycoprotein 75; melanoma antigen gp75; TRP-1; TRP1; tyrosinase-related protein 1
b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP; TYRP1; TYRRP