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|Tested species reactivity||Human , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues A(23) F P R L E P N S I D P E N C(36) of rat TrkB.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18402 detects Tyrosine Kinase Receptor B from human and rat samples.
PA1-18402 has been successfully used in immunohistochemistry procedures.
The PA1-18402 immunogen is a synthetic peptide corresponding to residues A(23) F P R L E P N S I D P E N C(36) of rat TrkB, conjugated to KLH.
Reconstitute with 100 ul of distilled water.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BDNF-tropomyosine receptor kinase B; BDNF/NT-3 growth factors receptor; GP145-TrkB/GP95-TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; TrkB; trkB tyrosine kinase; tropomyosin-related kinase B; tyrosine kinase receptor B
GP145-TrkB; NTRK2; RATTRKB1; Tkrb; trk-B; TRKB; TRKB1