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|Tested species reactivity||Mouse , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Extracellular domain of glycosylated mouse TrkB protein produced in CHO cells.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18403 detects Tyrosine Kinase Receptor B from mouse and rat samples.
PA1-18403 has been successfully used in immunohistochemistry and ELISA procedures.
The PA1-18403 immunogen is the extracellular domain of glycosylated mouse TrkB protein produced in CHO cells.
Reconstitute with 100 ul of distilled water.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BDNF/NT-3 growth factors receptor; GP145-TrkB/GP95-TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic tyrosine receptor kinase type 2; TrkB; trkB tyrosine kinase
GP145-TrkB/GP95-TrkB; Ntrk2; RATTRKB1; Tkrb; trk-B; Trkb; TRKB1