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This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified.
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Protein Aliases: FLJ23251; FLJ23251UBA5; ThiFP1; UBA5, ubiquitin-activating enzyme E1 homolog; Ubiquitin-activating enzyme 5; Ubiquitin-activating enzyme E1 domain-containing protein 1; ubiquitin-activating enzyme E1-domain containing 1; ubiquitin-like modifier activating enzyme 5; Ubiquitin-like modifier-activating enzyme 5; UFM1-activating enzyme
Gene Aliases: THIFP1; UBA5; UBE1DC1
UniProt ID: (Human) Q9GZZ9
Entrez Gene ID: (Human) 79876
Molecular Function: ubiquitin-protein ligase