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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:150 | - |
Flow Cytometry (Flow) |
1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Dog, Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI3D1 |
Immunogen |
Full length human recombinant protein of human UBE2J1 produced in HEK293T cell. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E2 ubiquitin-conjugating enzyme J1; HSUBC6e; MGC12555; NCUBE-1; non-canonical ubiquitin conjugating enzyme 1; Non-canonical ubiquitin-conjugating enzyme 1; ubiquitin conjugating enzyme E2, J1; Ubiquitin-conjugating enzyme E2 J1; ubiquitin-conjugating enzyme E2, J1; ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast); ubiquitin-conjugating enzyme E2, J1, U; Yeast ubiquitin-conjugating enzyme UBC6 homolog E
Gene Aliases: 0710008M05Rik; 1110030I22Rik; CGI-76; HSPC153; HSPC205; HSU93243; Ncube; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p; UBE2J1
UniProt ID: (Human) Q9Y385, (Mouse) Q9JJZ4
Entrez Gene ID: (Human) 51465, (Dog) 474993, (Rat) 297961, (Mouse) 56228
Molecular Function:
ubiquitin-protein ligase
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