|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to 15 residues near the C-terminus of human UBC13.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is HepG2 cell lysate or human small intestine tissue lysate.
Anti-Ubc13 is a monoclonal antibody specific to the ~19 kDa Ubc13 protein. Ubc13 is a ubiquitin conjugating enzyme that is complexed with a ubiquitin activating enzyme (E1), Mms2. The association of Mms2 to Ubc13 forms an active heterodimer that is involved in error-free post replicative DNA repair in yeast. Upon complexing with another conjugating enzyme variant, Uev1a, Ubc13 participates in the regulation of NF-kB signal transduction pathway in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.