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Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytidine monophosphokinase 1; UCK 1; UCK1; Uridine monophosphokinase 1; Uridine-cytidine kinase 1; URK1
Gene Aliases: UCK1; URK1
UniProt ID: (Human) Q9HA47
Entrez Gene ID: (Human) 83549
Molecular Function:
glycosyltransferase
kinase
nucleotide kinase
transferase
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