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Invitrogen
UHRF1 Recombinant Rabbit Monoclonal Antibody (1H2L41)
FIGURE: 1 / 3
UHRF1 Antibody (702830) in WB
Western blot analysis was performed on Modified whole cell extracts (1% SDS) (30 µg lysate) of HeLa (Lane 1) Hep G2 (Lane 2), HCT 116 (Lane 3), COLO 205 (Lane 4), Jurkat (Lane 5), MCF-7 (Lane 6), MDA-MB-231 (Lane 7), U-2 OS (Lane 8) and PANC-1 (Lane 9). The blots were probed with Anti-UHRF1 Recombinant Rabbit Monoclonal Antibody (Product # 702830, 1:200 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 90 kDa... View More
Product Details
702830
Product Specifications
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
1H2L41
Immunogen
Protein corresponding to human UHRF1 [126-285]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2725627
Product Specific Information
This antibody is predicted to react with Monkey, Dog, Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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