Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: liver-specific uridine phosphorylase; UDRPASE2; UPase 2; UPASE2; urdPase 2; Uridine phosphorylase 2; uridine phosphorylase-2
Gene Aliases: UDRPASE2; UP2; UPASE2; UPP2
UniProt ID: (Human) O95045
Entrez Gene ID: (Human) 151531