|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ERARGEELDED) corresponding to the C-terminus amino acids of FERMT3|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III . Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fermitin family homolog 3; fermitin family homolog 3 (Drosophila); FERMT3; KIND3; kindlin 3; Kindlin-3; MGC10966; MIG2-like protein; MIG2B; UNC-112 related protein 2; Unc-112-related protein 2; UNC112C; URP2; URP2SF
Gene Aliases: FERMT3; KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
UniProt ID: (Human) Q86UX7
Entrez Gene ID: (Human) 83706
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