Invitrogen

USP22 Recombinant Rabbit Monoclonal Antibody (ARC1498)

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USP22 Antibody in Western Blot (WB) — Western Blot analysis of USP22 performed on various cell lines using a USP22 monoclonal antibody (Product # MA5-35788) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000.

Product Details

MA5-35788

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Recombinant Monoclonal
Type	Antibody
Clone	ARC1498
Immunogen	A synthesized peptide derived from human USP22
Conjugate	Unconjugated
Form	Liquid
Concentration	0.857 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2849688

Target Information

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Deubiquitinating enzyme 22; Ubiquitin carboxyl-terminal hydrolase 22; ubiquitin specific protease 22; Ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; Ubiquitin-specific-processing protease 22

Gene Aliases: AI427806; KIAA1063; USP22; USP3L

UniProt ID: (Human) Q9UPT9, (Mouse) Q5DU02

Entrez Gene ID: (Human) 23326, (Mouse) 216825, (Rat) 303201

Molecular Function: cysteine protease