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UTS2 Antibody (MA5-55591) in WB
Western blot analysis of lysates from Rat brain, using UTS2 Recombinant Monoclonal Antibody (Product # MA5-55591) at 1:500 dilution followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
MA5-55591
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3B2M6
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 20-124 of human Urotensin II (UTS2).
Conjugate
Form
Liquid
Concentration
0.95 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Immunogen Sequence: SLPLLDSREI SFQLSAPHED ARLTPEELER ASLLQILPEM LGAERGDILR KADSSTNIFN PRGNLRKFQD FSGQDPNILL SHLLARIWKP YKKRETPDCF WKYCV
Target Information
Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: U-II; UII; urocortin 2; Urotensin II; Urotensin-2; urotensin-II
Gene Aliases: Ucn2; Uts2
UniProt ID: (Rat) Q9QZQ4
Entrez Gene ID: (Rat) 29180
response to hypoxia
negative regulation of glomerular filtration
positive regulation of cytosolic calcium ion concentration
negative regulation of heart rate
positive regulation of heart rate
positive regulation of fibroblast migration
positive regulation of circadian sleep/wake cycle, wakefulness
positive regulation of synaptic transmission, cholinergic
positive regulation of collagen biosynthetic process
response to testosterone
negative regulation of urine volume
negative regulation of renal sodium excretion
response to drug
positive regulation of cell differentiation
positive regulation of angiogenesis
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of vasodilation
positive regulation of circadian sleep/wake cycle, REM sleep
negative regulation of insulin secretion
positive regulation of fibroblast proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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