Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Ubiquitin is a highly conserved globular 76 amino acid protein of about 8.5 kDa molecular weight. It has a important role in the targeting of proteins for proteolytic degradation. Proteins to be degraded are covalantly coupled to the C-terminus of ubiquitin by means of ubiquitin ligases. The ubiquitin itself is frequently also ubiquitinated, producing a polyubiquitin chain.
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Protein Aliases: 40S ribosomal protein S27a; 60S ribosomal protein L40; Cat L; Cathepsin L; Cathepsin L1; Cathepsin L1 heavy chain; Cathepsin L1 light chain; CEP52; CP-2; Cyclic protein 2; epididymis luminal protein 112; furless; Large ribosomal subunit protein eL40; Major excreted protein; MEP; nackt; p39 cysteine proteinase; polyubiquitin C; Polyubiquitin-C; Procathepsin L; Small ribosomal subunit protein eS31; Ubiquitin; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein S27a; ubiquitin C; ubiquitin carboxyl extension protein 52; Ubiquitin carboxyl extension protein 80; Ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like; ubiquitin-52 amino acid fusion protein; Ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52; ubiquitin-CEP80; Ubiquitin-related; Ubiquitin-related 1; Ubiquitin-related 2; ubiquitin/60S ribosomal fusion protein
Gene Aliases: 0610006J14Rik; 1190035F06Rik; 2700054O04Rik; AI194771; CATHL; CATL; CEP52; CEP80; CTSL; CTSL1; D8Ertd21e; fs; Gm1863; HEL112; HMG20; HUBCEP52; L40; MEP; nkt; RPL40; RPS27A; S27A; TI-225; UBA52; UBA80; Ubb; UBC; UBCEP1; UBCEP2; UBCEP80