|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 296-326 amino acids from the central region of human Ubiquilin1|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with rat based on sequence homology.
PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hPLIC-1; PLIC-1; Protein linking IAP with cytoskeleton 1; Protein linking IAP with cytoskeleton-1; testicular tissue protein Li 219; Ubiquilin 1; Ubiquilin-1; UBQLN1
Gene Aliases: 1110046H03Rik; 1810030E05Rik; AU019746; C77538; D13Ertd372e; DA41; DSK2; PLIC-1; PLIC1; UBQLN1; UBQN; XDRP1
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