|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full-length human ubiquitin protein|
|Storage buffer||PBS, pH 7.6, with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C|
PA5-16829 targets Ubiquitin in IHC (P) applications and shows reactivity with Human samples.
The PA5-16829 immunogen is recombinant full-length human ubiquitin protein.
Ubiquitin (Ub) plays a very important role in regulated non-lysosomal ATP dependent protein degradation. The protein to be degraded is conjugated to Ub and the ubiquinated protein is then selectively degraded by a 26S complex, multicatalytic cytosolic and nuclear protease termed proteasome. The Ub-proteasome proteolytic pathway, which is a complex process, is implicated to be of great importance for regulating numerous cellular processes.
Protein Aliases: 40S ribosomal protein S27a; epididymis luminal protein 112; ubiquitin and ribosomal protein S27a; ubiquitin C; Ubiquitin carboxyl extension protein 80; Ubiquitin-40S ribosomal protein S27a; ubiquitin-CEP80
Gene Aliases: CEP80; HEL112; RPS27A; S27A; UBA80; UBC; UBCEP1; UBCEP80
UniProt ID: (Human) P62979
Entrez Gene ID: (Human) 6233