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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the C-terminal region of human urocortin|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Urocortin (UCN), a 40 amino acids neuropeptide widely distributed in the central nervous system (CNS), belongs to a family of structurally related peptides including corticotrophin releasing factor (CRF), sauvagine and urotensin I. Urocortin is derived from a larger precursor protein (pro-urocortin, also named corticotensin). Urocortin has biological actions similar to CRF such as stress-related endocrine, autonomic and behavioral responses in mammalian species. It is a potent stimulator of adrenocorticotropic hormone (ACTH) secretion by corticotroph cells from the anterior pituitary in vitro and in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Corticotensin; prepro-urocortin; preproprotein; UI; UROC; Urocortin; urocortin, preproprotein
Mpv17; UCN; Ucn1; UI; UROC