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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 119 of Human V-ATPase F|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27516 targets V-ATPase F in WB applications and shows reactivity with Human samples.
The PA5-27516 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 119 of Human V-ATPase F.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
14 kD; 14kD subunit; adenosinetriphosphatase 14k chain; ATP6S14; ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F; ATPase, vacuolar, 14 kD; H(+)-transporting two-sector ATPase; H(+)-transporting two-sector ATPase, 14kD subunit; V-ATPase 14 kDa subunit; V-ATPase F subunit; V-ATPase subunit F; V-type proton ATPase subunit F; vacuolar; vacuolar ATP synthase subunit F; vacuolar proton pump F; vacuolar proton pump F subunit; Vacuolar proton pump subunit F; VATF; Vma7
ATP6S14; ATP6V1F; VATF; Vma7