|Tested species reactivity||Human, Pig|
|Published species reactivity||Mouse, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Crude human synaptic immunoprecipitate.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||1:1,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
MA1-24955 detects Synaptobrevin from human and porcine samples. MA1-24955 will not react with rat.
MA1-24955 has been successfully used in immunohistochemistry (paraffin), and Western blot procedures.
The MA1-24955 immunogen is crude human synaptic immunoprecipitate.
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice.
MA1-24955 was used in immunohistochemistry to study the effects of PHD-1 deficiency on neuroepithelial body hyperplasia in a murine model
|Pan J,Yeger H,Ratcliffe P,Bishop T,Cutz E||Advances in experimental medicine and biology (758:149)||2012|
p63 expression as a new prognostic marker in Merkel cell carcinoma.
MA1-24955 was used in immunohistochemistry to study p63 expression as a prognostic marker in Merkel cell carcinoma
|Asioli S,Righi A,Volante M,Eusebi V,Bussolati G||Cancer (110:640)||2007|