This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Ventral anterior homeobox 1
Gene Aliases: MCOPS11; VAX1
UniProt ID: (Human) Q5SQQ9
Entrez Gene ID: (Human) 11023
Molecular Function: homeodomain transcription factor