The protein encoded by VBP1 interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms.
Protein Aliases: HIBBJ46; prefoldin 3; Prefoldin subunit 3; RP13-228J13.4; VBP-1; VHL binding protein-1; von Hippel-Lindau binding protein 1; von Hippel-Lindau-binding protein 1
Gene Aliases: HIBBJ46; PFD3; PFDN3; VBP-1; VBP1
UniProt ID: (Human) P61758
Entrez Gene ID: (Human) 7411
Molecular Function: chaperone