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|Tested species reactivity||Human|
|Published species reactivity||Rat, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Full length protein (Human)|
|Storage buffer||PBS with 0.1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Flow Cytometry (Flow)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-34975 detects VCAM1 from human samples.
MA1-34975 has been successfully used in ELISA, Flow cytometry, and immunoprecipitation applications.
The MA1-34975 immunogen is: Full length protein (Human)
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Differentiation of human mesenchymal stem cells: the potential mechanism for estrogen-induced preferential osteoblast versus adipocyte differentiation.
MA1-34975 was used in flow cytometry to investigate the regulatory role of estrogen signaling pathways in the differentiation of mesenchymal stem cells in vitro
|Zhao JW,Gao ZL,Mei H,Li YL,Wang Y||The American journal of the medical sciences (341:460)||2011|
Gliotoxin inhibits neointimal hyperplasia after vascular injury in rats.
MA1-34975 was used in flow cytometry to study the effect of gliotoxin on neointimal hyperplasia in rats
|Pozo M,Izquierdo MC,de Nicolás R,Egido J,Ortiz A,González-Cabrero J||Journal of vascular research (46:278)||2009|
Simvastatin inhibits the migration and adhesion of monocytic cells and disorganizes the cytoskeleton of activated endothelial cells.
MA1-34975 was used in flow cytometry to investigate the effect of simvastatin on monocytic cells and endothelial cell cytoskeleton
|Pozo M,de Nicolás R,Egido J,González-Cabrero J||European journal of pharmacology (548:53)||2006|
Human adult craniofacial muscle-derived cells: neural-cell adhesion-molecule (NCAM; CD56)-expressing cells appear to contain multipotential stem cells.
MA1-34975 was used in immunocytochemistry to characterize muscle-derived multipotential stem cells
|Sinanan AC,Hunt NP,Lewis MP||Biotechnology and applied biochemistry (40:25)||2004|
Platelet factor 4-induced neutrophil-endothelial cell interaction: involvement of mechanisms and functional consequences different from those elicited by interleukin-8.
MA1-34975 was used in blocking/activating experiment to characterize the role of Platelet factor 4 (PF-4) in the interaction between neutrophil and endothelial cells
|Petersen F,Bock L,Flad HD,Brandt E||Blood (94:4020)||1999|
CD106; CD106 antigen; DKFZp779G2333; MGC99561; vascular cell adhesion protein 1
CD106; INCAM-100; L1CAM; VCAM1