MA5-14614 targets Vitamin D Receptor in GS and WB applications and shows reactivity with Amphibian, Chicken, Fish, Hamster, Human, mouse, Porcine, and Rat samples.
The MA5-14614 immunogen is vitamin D receptor protein from chicken intestine.
VDR is a member of super family of steroid hormone receptors. It is known to play role in cellular growth and differentiation, calcium and phosphorus metabolism and bone remodeling. Human breast carcinomas, leukemias, and prostatic carcinoma cells express VDR, which can modify their growth and differentiation. In avians, VDR appears as a doublet of 58kDa and 60kDa.
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Protein Aliases: 1; 1,25-dihydroxyvitamin D3 receptor; 25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1; protein phosphatase 1, regulatory subunit 163; VDR; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; Vitamin D3 receptor
Gene Aliases: I79_025795; NR1I1; PPP1R163; VDR