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Proteintech
VE-cadherin/CD144 Polyclonal Antibody
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Product Details
32332-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VE-cadherin/CD144 fusion protein Eg0921
Conjugate
Form
Liquid
Concentration
350 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: DWIWNQMHID EEKNESLPHY VGKIKSNVNR QNAKYVLQGE FAGKIFGVDA NTGNVLAYER LDREKVSEYF LTALIVDKNT NKNLEQPSSF TVKVHDINDN WPVFSHQVFN ASVPEMSAIG TSVIRVTAVD ADDPTVAGHA TVLYQIVKGN EYFSIDNSGL IFTKIKNLDR EKQAEYKIVV ETQDALGLRG ESGTATVMIR LEDINDNFPV FTQSTYTFSV PEDIRVGKPL GFLTVVDPDE PQNRMTKYSI MQGEYRDTFT IETDPKRNEG IIKPTKSLDY EVIQQYTFYI EATDPTIRYE YLSSTSGKNK AMVTINVLDV DEPPVFQRHF YHFKLPENQK KPLIGTVVAK DPDKAQRSIG YSIRKTSDRG QFFRITKQGN IYNEKELDRE TYAWYNLTVE ANELDSRGNP VGKESIVQVY IEVLDENDNP PEFAQPYEPK VCENAAQGKL VVQISATDKD VVPVNPKFKF ALKNEDSNFT LINNHDNTAN ITVKYGQFNR EHAKFHYLPV LISDNGVPSL TGTSTLTVGV CKCNEQGEFT FCEEMAA
Target Information
VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7B4/cadherin-5; Cadherin-5; CD144; Vascular endothelial cadherin; VE-cadherin
Gene Aliases: 7B4; AA408225; Cd144; Cdh5; VE-Cad; Vec; VEcad; VECD
UniProt ID: (Mouse) P55284
Entrez Gene ID: (Mouse) 12562, (Rat) 307618
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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