Product References
Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Nature communications
Meçe O,Houbaert D,Sassano ML,Durré T,Maes H,Schaaf M,More S,Ganne M,García-Caballero M,Borri M,Verhoeven J,Agrawal M,Jacobs K,Bergers G,Blacher S,Ghesquière B,Dewerchin M,Swinnen JV,Vinckier S,Soengas MS,Carmeliet P,Noël A,Agostinis P
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Thu May 19 00:00:00 EDT 2022
VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome.
Life science alliance
Cioffi S,Flore G,Martucciello S,Bilio M,Turturo MG,Illingworth E
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Mon Oct 10 00:00:00 EDT 2022
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level.
Cell research
Wang X,Yang L,Wang YC,Xu ZR,Feng Y,Zhang J,Wang Y,Xu CR
14-5988 was used in Immunohistochemistry-immunofluorescence to study cell lineage differentiation during hepatogenesis using single-cell RNA sequencing of whole human and mouse fetal livers throughout development.
Tue Dec 01 00:00:00 EST 2020
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.
The Journal of pathology
Sato T,Paquet-Fifield S,Harris NC,Roufail S,Turner DJ,Yuan Y,Zhang YF,Fox SB,Hibbs ML,Wilkinson-Berka JL,Williams RA,Stacker SA,Sly PD,Achen MG
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Wed Jun 01 00:00:00 EDT 2016
VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.
The Journal of pathology
Sato T,Paquet-Fifield S,Harris NC,Roufail S,Turner DJ,Yuan Y,Zhang YF,Fox SB,Hibbs ML,Wilkinson-Berka JL,Williams RA,Stacker SA,Sly PD,Achen MG
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Wed Jun 01 00:00:00 EDT 2016
A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.
Pharmaceuticals (Basel, Switzerland)
Tagaram HR,Desai D,Li G,Liu D,Rountree CB,Gowda K,Berg A,Amin S,Staveley-O'Carroll KF,Kimchi ET
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Thu Mar 24 00:00:00 EDT 2016
A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.
Pharmaceuticals (Basel, Switzerland)
Tagaram HR,Desai D,Li G,Liu D,Rountree CB,Gowda K,Berg A,Amin S,Staveley-O'Carroll KF,Kimchi ET
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunohistochemistry
Thu Mar 24 00:00:00 EDT 2016
G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling.
Cell reports
Majumder S,Zhu G,Xu X,Senchanthisai S,Jiang D,Liu H,Xue C,Wang X,Coia H,Cui Z,Smolock EM,Libby RT,Berk BC,Pang J
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Western Blot
Tue Dec 06 00:00:00 EST 2016
Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics.
Transplantation
Iwami D,Brinkman CC,Bromberg JS
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Ephrin-B2 controls PDGFRβ internalization and signaling.
Genes & development
Nakayama A,Nakayama M,Turner CJ,Höing S,Lepore JJ,Adams RH
14-5988 was used in Western Blotting to show that ephrin-B2 is an important regulator of PDGFRβ endocytosis, acting as a molecular switch controlling the downstream signaling activity of this receptor in mural cells.
Sun Dec 01 00:00:00 EST 2013
Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature.
PloS one
Dellinger MT,Meadows SM,Wynne K,Cleaver O,Brekken RA
14-5988 was used in Immunohistochemistry to show that the proper development of the lymphatic vasculature requires VEGFR2 expression by lymphatic endothelium.
Tue Apr 08 00:00:00 EDT 2014
RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.
The Journal of clinical investigation
Lapinski PE,Kwon S,Lubeck BA,Wilkinson JE,Srinivasan RS,Sevick-Muraca E,King PD
14-5988 was used in Immunofluorescence to reveal a role for RASA1, a Ras GTPase-activating protein, as a physiological negative regulator of lymphatic endothelial cell growth.
Wed Feb 01 00:00:00 EST 2012
Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cell death and differentiation
Cesca F,Yabe A,Spencer-Dene B,Scholz-Starke J,Medrihan L,Maden CH,Gerhardt H,Orriss IR,Baldelli P,Al-Qatari M,Koltzenburg M,Adams RH,Benfenati F,Schiavo G
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Western Blot
Wed Feb 01 00:00:00 EST 2012
Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cell death and differentiation
Cesca F,Yabe A,Spencer-Dene B,Scholz-Starke J,Medrihan L,Maden CH,Gerhardt H,Orriss IR,Baldelli P,Al-Qatari M,Koltzenburg M,Adams RH,Benfenati F,Schiavo G
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Western Blot
Wed Feb 01 00:00:00 EST 2012
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release.
Journal of immunology (Baltimore, Md. : 1950)
Jayaraman P,Parikh F,Lopez-Rivera E,Hailemichael Y,Clark A,Ma G,Cannan D,Ramacher M,Kato M,Overwijk WW,Chen SH,Umansky VY,Sikora AG
14-5988 was used in Flow cytometry/Cell sorting to suggest a critical role for tumor-expressed inducible NO synthase in recruitment and induction of functional myeloid-derived suppressor cells.
Fri Jun 01 00:00:00 EDT 2012
Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
PloS one
Izumi N,Helker C,Ehling M,Behrens A,Herzog W,Adams RH
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunofluorescence
Tue Apr 02 00:00:00 EDT 2013
Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
PloS one
Izumi N,Helker C,Ehling M,Behrens A,Herzog W,Adams RH
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Immunofluorescence
Tue Apr 02 00:00:00 EDT 2013
VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis.
Cell research
Zhang L,Zhou F,Han W,Shen B,Luo J,Shibuya M,He Y
14-5988 was used in Western Blotting to indicate that signaling mediated via VEGFR-3 activation by its cognate ligands (VEGF-C/-D) is not required for angiogenesis.
Wed Dec 01 00:00:00 EST 2010
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization.
Cancer cell
Tvorogov D,Anisimov A,Zheng W,Leppänen VM,Tammela T,Laurinavicius S,Holnthoner W,Heloterä H,Holopainen T,Jeltsch M,Kalkkinen N,Lankinen H,Ojala PM,Alitalo K
14-5988 was used in Western Blotting to show that combined use of antibodies blocking ligand binding and receptor dimerization improves VEGFR inhibition and results in stronger inhibition of endothelial sprouting and vascular network formation in vivo.
Tue Dec 14 00:00:00 EST 2010
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Western Blot
Mon Jun 28 00:00:00 EDT 2010
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 14-5988-82) in Western Blot
Mon Jun 28 00:00:00 EDT 2010
Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells.
Cancer gene therapy
Kanehira M,Xin H,Hoshino K,Maemondo M,Mizuguchi H,Hayakawa T,Matsumoto K,Nakamura T,Nukiwa T,Saijo Y
14-5988 was used in Immunohistochemistry to indicate that mesenchymal stem cells can serve as a vehicle of gene therapy for targeting multiple lung metastatic tumours.
Thu Nov 01 00:00:00 EDT 2007
Vascular endothelial growth factor-D activates VEGFR-3 expressed in osteoblasts inducing their differentiation.
The Journal of biological chemistry
Orlandini M,Spreafico A,Bardelli M,Rocchigiani M,Salameh A,Nucciotti S,Capperucci C,Frediani B,Oliviero S
14-5988 was used in Immunofluorescence in immunohistochemistry on frozen tissues to show that in the long bones of newborn mice, vascular endothelial growth factor (VEGF)-D and VEGFR-3 are expressed in the osteoclasts of the growing plate.
Fri Jun 30 00:00:00 EDT 2006