This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LRKQRTNFHQ RFESPESQAS AEQPEM
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: FLJ12930; Hbeta58 homolog; hVPS26; OTTHUMP00000019721; vacuolar protein sorting 26 homolog A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; VPS26 retromer complex comonent A; VPS26 retromer complex component A
Gene Aliases: HB58; Hbeta58; PEP8A; VPS26; VPS26A
UniProt ID: (Human) O75436
Entrez Gene ID: (Human) 9559
Molecular Function: membrane traffic protein