MA1-828 detects VRK1 from human and mouse samples.
MA1-828 has been successfully used in Western blot, immunofluorescence, and immunohistochemistry applications. For Western blotting, it is recommended to block with 3% BSA (not milk).
The MA1-828 immunogen is recombinant fusion protein GST-VRK1.
Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC117401; MGC138280; Serine/threonine-protein kinase 51PK; Serine/threonine-protein kinase VRK1; Vaccinia related kinase 1; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1
Gene Aliases: 51PK; PCH1; PCH1A; VRK1