Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product is supplied at 1 mL (100 µL/mL).
Application Notes: Western blot - non-reduced sample treatment and SDS-Page was used. The band sizes are 45 kDa and fainter band of 37 kDa in transfected cells and 37 kDa in granulocytes. Functional Assay - Antibody 1A5 showed inhibition of Fc eta RI-mediated degranulation by RBL-2H3 cells transfected with SIRL-1. The percentage of inhibition of degranulation by SIRL-1 was calculated by (OD405 TNP stimulation - OD405 TNP with SIRL-1 crosslinking)/(OD405 TNP stimulation - OD405 spontaneous release) x 100.
VSTM1 (V-Set And Transmembrane Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is LILRB1.
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Protein Aliases: LAIR homolog; OSCAR-like transcript-1; Signal inhibitory receptor on leukocytes-1; SIRL-1; V-set and transmembrane domain-containing protein 1
Gene Aliases: SIRL-1; SIRL1; UNQ3033; UNQ3033/PRO9835; VSTM1
UniProt ID: (Human) Q6UX27
Entrez Gene ID: (Human) 284415
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