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Invitrogen
VWF Recombinant Rabbit Monoclonal Antibody (ARC0716)
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
VWF Antibody (MA5-35178) in IHC (P)
Immunohistochemistry analysis of VWF in paraffin-embedded human esophageal. Samples were incubated with VWF Monoclonal antibody (Product # MA5-35178) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
MA5-35178
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC0716
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1150-1300 of human von Willebrand factor (VWF) (P04275)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849083
Product Specific Information
Immunogen sequence: APACQVTCQH PEPLACPVQC VEGCHAHCPP GKILDELLQT CVDPEDCPVC EVAGRRFASG KKVTLNPSDP EHCQICHCDV VNLTCEACQE PGGLVVPPTD APVSPTTLYV EDISEPPLHD FYCSRLLDLV FLLDGSSRLS EAEFEVLKAF V
Target Information
Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coagulation Factor VIII; coagulation factor VIII VWF; factor viii related antigen; von Willebrand Disease (vWD); von Willebrand factor; vWF
Gene Aliases: 6820430P06Rik; AI551257; B130011O06Rik; C630030D09; F8VWF; VWD; VWF
UniProt ID: (Human) P04275, (Mouse) Q8CIZ8
Entrez Gene ID: (Human) 7450, (Mouse) 22371
platelet degranulation
cell adhesion
blood coagulation
blood coagulation, intrinsic pathway
hemostasis
response to wounding
platelet activation
extracellular matrix organization
cell-substrate adhesion
response to immobilization stress
protein homooligomerization
liver development
placenta development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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