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Alomone Labs, LTD
Vasopressin V1A Receptor (AVPR1A) Polyclonal Antibody
FIGURE: 1 / 3
Vasopressin V1A Receptor (AVPR1A) Antibody (AVR-010-GP-200UL) in IHC (F)
Expression of V1aR in rat medial septum. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Guinea Pig Anti-Vasopressin V 1A Receptor (AVPR1A) Antibody (#AVR-010-GP) (1:200), followed by goat anti-guinea pig - Alexa Fluor-594. A. V1aR immunoreactivity (red) appears in neuronal outlines (arrows). B. Pre-incubation of the antibody with Vasopressin V 1A Receptor (AVPR1A) Blocking Pe... View More
Product Details
AVR-010-GP-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Guinea pig
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide KFAKDDSDSMSRR, corresponding to amino acid residues 378-390 of rat AVPR1A. Intracellular, C-terminus.
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: KFAKDDSDSMSRR
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Vasopressin receptor 1a (AVPR1A) is a receptor for arginine vasopressin. The activity of this receptor is mediated by G-proteins which activate a phosphatidyl-inositol-calcium second messenger system. AVPR1A has been involved in social behaviors, including affiliation and attachment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; AVPR V1a; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a arginine vasopressin receptor; V1a receptor; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor; Vasopressin V1aR
Gene Aliases: AVPR; AVPR V1a; AVPR1; AVPR1A; V1a; V1aR
UniProt ID: (Human) P37288, (Rat) P30560, (Mouse) Q62463
Entrez Gene ID: (Human) 552, (Rat) 25107, (Mouse) 54140
regulation of systemic arterial blood pressure by vasopressin
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
generation of precursor metabolites and energy
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
negative regulation of female receptivity
grooming behavior
blood circulation
positive regulation of cell proliferation
positive regulation of heart rate
positive regulation of glutamate secretion
myotube differentiation
calcium-mediated signaling
telencephalon development
positive regulation of cell growth
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
cellular response to hormone stimulus
social behavior
positive regulation of renal sodium excretion
cellular response to water deprivation
maternal behavior
sperm ejaculation
penile erection
positive regulation of vasoconstriction
response to corticosterone
negative regulation of transmission of nerve impulse
response to peptide
response to organic substance
response to inorganic substance
positive regulation of urine volume
positive regulation of blood pressure
positive regulation of glycogen catabolic process
regulation of corticotropin secretion
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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