MA5-15664 targets WDR5 in WB applications and shows reactivity with Human samples.
The MA5-15664 immunogen is purified recombinant fragment of human WDR5 expressed in E. Coli.
MA5-15664 detects WDR5 which has a predicted molecular weight of approximately 36.6kDa.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp , which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
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Protein Aliases: BIG-3; BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5; WDR5
Gene Aliases: BIG-3; BIG3; CFAP89; SWD3; WDR5
UniProt ID: (Human) P61964
Entrez Gene ID: (Human) 11091