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WDR61 Antibody (TA807588) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WDR61 (RC203963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-WDR61. Positive lysates LY410745 (100 µg) and LC410745 (20 µg) can be purchased separately from OriGene.
Product Details
TA807588
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1D4
Immunogen
Human recombinant protein fragment corresponding to amino acids 92-305 of human WDR61 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; Superkiller complex protein 8; WD repeat-containing protein 61
Gene Aliases: REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3
Entrez Gene ID: (Human) 80349
transcription, DNA-templated
Wnt signaling pathway
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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