For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
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Protein Aliases: Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
Gene Aliases: 2610003I18Rik; 2610312E17Rik; C79984; HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/MEP50; WD45; WDR77